Fibroblast Growth Factor 1 Promotes Rat Stem Leydig Cell Development
نویسندگان
چکیده
منابع مشابه
Fibroblast Growth Factor-1 vs. Fibroblast Growth Factor-2 in Ischemic Skin Flap Survival in a Rat Animal Model
BACKGROUND One of the main challenges in skin flap surgery is tissue ischemia and following necrosis. The present study compares the effects of fibroblast growth factors 1 and 2 on increasing cutaneous vasculature, improving ischemia, and preventing distal necrosis in ischemic skin flaps in rat model. METHODS Thirty rats were allocated into 3 groups (n=10) and 2×8 cm dorsal rando...
متن کاملParathyroid Hormone-Related Protein Promotes Rat Stem Leydig Cell Differentiation
The regulatory factors for stem Leydig cell development are largely unknown. Herein, we reported that parathyroid hormone-related protein (PTHrP) may be a factor to regulate this process. The effects of PTHrP on rat stem Leydig cell proliferation and differentiation were investigated using a stem Leydig cell culture system and an ethane dimethane sulfonate (EDS)-treated in vivo Leydig cell rege...
متن کاملO-20: The Combination of Basic Fibroblast Growth Factor and Follicular Stimulating Hormone Promotes Human Follicle Development In Vitro Culture
Background Fertility preservation is an important part of scientific study in the field of reproductive medicine. Ovarian cryopreservation and in vitro follicles culture provide option for fertility conservation in older women or cancer patients. Basic fibroblast growth factor (bFGF) or FGF-2, is member of fibroblast growth factors family which play critical roles in cell migration proliferatio...
متن کاملAldosterone Blocks Rat Stem Leydig Cell Development In Vitro
Aldosterone (ALDO) is a primary endogenous mineralocorticoid, appearing as the main hormone controlling sodium and water homeostasis. Its emerging role in the development of many organs has gained interest over the past few years. In the testis, Leydig cells contain mineralocorticoid receptors and ALDO stimulates androgen synthesis via the mineralocorticoid receptors in rat adult Leydig cells. ...
متن کاملHepatocyte growth factor-modulated rat Leydig cell functions.
Hepatocyte growth factor (HGF) regulates many cellular functions acting through c-Met, its specific tyrosine kinase receptor. We previously reported that in prepuberal rats HGF is secreted by the peritubular myoid cells during the entire postnatal testicular development and by the Sertoli cells only at puberty. We have also demonstrated that germ cells at different stages of development express...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Frontiers in Endocrinology
سال: 2019
ISSN: 1664-2392
DOI: 10.3389/fendo.2019.00118